Centro ricerche Imaging Cardiovascolare Multimodale Integrato
DIRETTORE
COORDINATORI
- Dott Michele Tomaselli (Ecocardiografia);
- Dott. Marzia Olivieri (TC Cuore);
- Dott.ssa Camilla Torlasco (RM Cuore)
ÉQUIPE
- Dott.ssa Claudia Baratto
- Prof. Sergio Caravita
- Dott. Andrea Cascella
- Dott.ssa Samantha Fisicaro
- Dott.ssa Mara Gavazzoni
- Dott.ssa Francesca Heilbron
- Prof.ssa Denisa Muraru
- Dott. Giorgio Oliverio
- Dott. Marco Penso
- Dott. Francesco Perelli
- Dott.ssa Valeria Rella
- Dott.ssa Camilla Torlasco
ATTIVITÀ DI RICERCA
L’attività del Centro di Ricerca su Imaging Cardiovascolare Multimodale Integrato è principalmente rivolta allo studio del valore diagnostico e prognostico aggiunto delle nuove tecnologie di imaging cardiovascolare non invasivo, applicazioni dell’intelligenza artificiale all’imaging cardiovascolare, utilizzo di tecniche di realtà artificiale e realtà estesa per aumentare la capacità diagnostica dell’imaging cardiovascolare noninvasivo, valutazione storia naturale e markers prognostici nei pazienti con cardiopatie valvolari, ricerca dei predittori di morte cardiaca improvvisa in pazienti con cardiopatia strutturale, valutazione della funzione ventricolare destra, valutazione e significato prognostico della funzione degli atri.
Il Centro di Ricerca su Imaging Cardiovascolare Multimodale funge inoltre da core-lab ecocardiografico per studi clinici organizzati da Auxologico o commissionati dall’industria e da altre Istituzioni scientifiche.
Il Centro di Ricerca su Imaging Cardiovascolare Multimodale collabora attivamente con l’industria ed ha formali contratti di ricerca con GE Healthcare (Horten, Norvegia), Philips Medical Systems (Andover, MA, USA), EsaOte SpA (Genova Italia), TomTec Imaging Systems (Unterschleissen, Germania).
Il Centro di Ricerca su Imaging Cardiovascolare Multimodale ha collaborazioni di ricerca con il National Institute of Health (USA), l’Università di Chicago (USA), l’Università Semmelweiss di Budapest (Ungheria), l’Università Carol Davila di Bucharest (Romania)
Il Centro di Ricerca su Imaging Cardiovascolare Multimodale si avvale del contributo di 2 dottorandi di ricerca, 1 Bioscientist e di diversi ricercatori che provengono da altre università italiane e straniere (Romania, Giappone, Montenegro).
MALATTIE OGGETTO DI RICERCA
- Cardiopatia ischemica;
- Insufficienza tricuspidale;
- Insufficienza mitralica;
- Stenosi aortica;
- Fibrillazione atriale;
- Cardiomiopatia ipertrofica;
- Amiloidosi cardiaca;
- Scompenso cardiaco a frazione d’eiezione conservata;
- Cuore d’atleta;
- Cardiopatia ipertensiva;
- Ipertensione polmonare.
RISULTATI DI PARTICOLARE IMPORTANZA RAGGIUNTI
Pubblicazioni (ultimi 2 anni)
2022
- Fratianni G, Malfatto G, Perger E, Facchetti L, Pini L, Bosco M, Cernigliaro F, Perego GB, Facchini M, Badano LP, Parati G. Lung Ultrasound in Patients with SARS-COV-2 Pneumonia: Correlations with Chest CT, Respiratory impairment and Inflammatory Cascade. J Cardiovasc Ultrasound 2022;41:1465-73 doi: 10.1002/jum.15831. PMID: 34533859.
- Russo G, Taramasso M, Pedicino D, Gennari M, Gavazzoni M, Pozzoli A, Murrau D, Badano LP, Metra M, Maisano F. Challenges and future perspectives of transcatheter tricuspid valve interventions: adopt old strategies or adapt to the new chances? Eur J Heart Fail 2022; 24: 442-54 doi: 10.1002/ejhf.2398. PMID: 34894039
- Florescu DR, Muraru D, Florescu C, Volpato V, Caravita S, Perger E, Bălșeanu TA, Parati G, Badano LP. Right heart chambers geometry and function in patients with the atrial and the ventricular phenotypes of functional tricuspid regurgitation. Eur Heart J Cardiovasc Imaging. 2022;23:930-940. doi: 10.1093/ehjci/jeab211. PMID: 34747460.
- Killekar A, Grodecki K, Lin A, Cadet S, McElhinney P, Razipour A, Chan C, Pressman BD, Julien P, Chen P, Simon J, Maurovich-Horvat P, Gaibazzi N, Thakur U, Mancini E, Agalbato C, Munechika J, Matsumoto H, Menè R, Parati G, Cernigliaro F, Nerlekar N, Torlasco C, Pontone G, Dey D, Slomka P. Rapid quantification of COVID-19 pneumonia burden from computed tomography with convolutional long short-term memory networks. J Med Imaging (Bellingham). 2022;9:054001. doi: 10.1117/1.JMI.9.5.054001. PMID: 36090960
- Merlo M, Porcari A, Pagura L, Cameli M, Vergaro G, Musumeci B, Biagini E, Canepa M, Crotti L, Imazio M, Forleo C, Cappelli F, Favale S, Di Bella G, Dore F, Lombardi CM, Pavasini R, Rella V, Palmiero G, Caiazza M, Albanese M, Guaricci AI, Branzi G, Caponetti AG, Saturi G, La Malfa G, Merlo AC, Andreis A, Bruno F, Longo F, Sfriso E, Di Ienno L, De Carli G, Giacomin E, Spini V, Milidoni A, Limongelli G, Autore C, Olivotto I, Badano L, Parati G, Perlini S, Metra M, Emdin M, Rapezzi C, Sinagra G. A national survey on prevalence of possible echocardiographic red flags of amyloid cardiomyopathy in consecutive patients undergoing routine echocardiography: study design and patients characterization - the first insight from the AC-TIVE Study. Eur J Prev Cardiol. 2022;29:e173-e177. doi: 10.1093/eurjpc/zwab127. PMID: 34499711.
- Ricci F, Bufano G, Galusko V, Sekar VB, Benedetto U, Awad WI, Kennon S, di Mauro M, Gallina S, Ionescu A, Badano L, Khanji MY. Tricuspid regurgitation management: a systematic review of clinical practice guidelines and recommendations. Eur Heart J Qual care Clin Outcomes 2022; 8: 238-48 DOI: 10.1093/ehjqcco/qcab081 PMID: 34878111
- Scorsin M, Andreas M, Corona S, Guta AC, Aruta P, Badano LP. Novel transcatheter mitral prosthesis designed to preserve physiological ventricular flow dynamics. Ann Thorac Surg. 2022; 113(2): 593-9 Apr 7:S0003-4975(21)00646-9. doi: 10.1016/j.athoracsur.2021.03.067. PMID: 33838122.
- Florescu DR, Muraru D, Volpato V, Gavazzoni M, Caravita S, Tomaselli M, Ciampi P, Florescu C, Bălșeanu TA, Parati G, Badano LP. Atrial Functional Tricuspid Regurgitation as a Distinct Pathophysiological and Clinical Entity: No Idiopathic Tricuspid Regurgitation Anymore. J Clin Med. 2022;11:382. doi: 10.3390/jcm11020382. PMID: 35054074
- Torlasco C, Castelletti S, Soranna D; Volpato V, Figliozzi S, Menacho K, Cernigliaro F, Zambon A, Kellman P, Moon JC, Badanp LP, Parati G. The EFFECTIVE study: development and application of a question-driven, time-effective cardiac magnetic resonance scanning protocol. JAHA 2022; 11: e022605 doi: 10.1161/JAHA.121.022605. PMID: 34970923
- Senage T, Paul A, Le Torneau T, Fellah-Hebia I, Vadori M, Bashir S, Galiñanes M, Bottio T, Gerosa G, Evangelista A, Badano LP, Nassi A, Costa C, Galli C, Manji RA, Cueff de Monchy C, Piriou N, Capoulade R, Serfati J-M, Guimbretière G, Dantan E, Ruiz-Majoral A, Coste du Fou G, Leviatan Ben-Aryes S, Govani L, Yehuda S, Bachar S, Ron Amon A, YU H, Iop L, Casos K, Kuguel SG, Blasco-Lucas A, Permanyer E, Sbraga F, Llatjos R, Moreno-Gonzales G, Sánchez-Martínez M, breimer ME, Holgersson J, Teneberg S, Pascual-Gilabert M, Nonell-Canals A, Takeuchi Y, Chen X, Mañez R, Roussel J-C, Soulillou J-P, Cozzi E, Padler-Karavani V. Early antibody responses against glycans of bioprosthetic heart valves support their eventual calcification. Nature Medicine 2022 28: 283-294 doi: 10.1038/s41591-022-01682-w. PMID: 35177855
- Lancellotti P, Pibarot P, Chambers J, La Canna G, Pepi M, Dulgheru R, Dweck M, Delgado V, Garbi M, Vannan M, Montaigne D, Badano L, Maurovitch Horvat P, Pontone G, Vahanian A, Donal E, Cosyns B. Multi-modality imaging assessment of native valvular regurgitation: an EACVI and ESC council of valvular heart disease position paper. Eur Heart J Cardiovasc Imaging 2022; 23: e171-e232 doi: 10.1093/ehjci/jeab253.PMID: 35292799
- Hahn RT, Donal E, Muraru D, et al. Functional tricuspid regurgitation: recent advances in thepathophysiology, severity grading and outcome. Eur Heart J Cardiovasc Imaging 2022;23:913-29 doi: 10.1093/ehjci/jeac009. PMID: 35157070
- Addetia K, Miyoshi T, Amuthan V, Citro R, Daimon M, Gutierrez Fajardo P, Kasliwal RR, Kirkpatrick JN, Monaghan MJ, Muraru D, Ogunyankin KO, Park SW, Ronderos RE, Sadeghpour A, Scalia GM, Takeuchi M, Tsang W, Tucay ES, Tude Rodrigues AC, Zhang Y, Hitschrich N, Blankenhagen M, Degel M, Schreckenberg M, Mor-Avi V, Asch FM, Lang RM; WASE Investigators. Normal Values of Left Ventricular Size and Function on Three-Dimensional Echocardiography: Results of the World Alliance Societies of Echocardiography Study. J Am Soc Echocardiogr. 2022;35:449-59 doi: 10.1016/j.echo.2021.12.004
- Merlo M, Pagura L, Porcari A, Cameli M, Vergaro G, Musumeci B, Biagini E, Canepa M, Crotti L, Imazio M, Forleo C, Cappelli F, Perfetto F, Favale S, Di Bella G, Dore F, Girardi F, Tomasoni D, Pavasini R, Rella V, Palmiero G, Caiazza M, Carella MC, Igoren Guaricci A, Branzi G, Caponetti AG, Saturi G, La Malfa G, Merlo AC, Andreis A, Bruno F, Longo F, Rossi M, Varrà GG, Saro R, Di Ienno L, De Carli G, Giacomin E, Arzilli C, Limongelli G, Autore C, Olivotto I, Badano L, Parati G, Perlini S, Metra M, Emdin M, Rapezzi C, Sinagra G. Unmasking the prevalence of amyloid cardiomyopathy in the real world: results from Phase 2 of the AC-TIVE study, an Italian nationwide survey. Eur J Heart Fail. 2022;24:1377-1386. doi: 10.1002/ejhf.2504. PMID: 35417089.
- Badano LP, Tomaselli M, Muraru D. Shedding light on the pathophysiology of non-valvular atrial fibrillation as a primary cause of the regurgitation of atrio-ventricular valves. Eur Heart J Cardiovasc Imaging 2022;23:956-7 DOI: 0.1093/ehjci/jeac080. PMID: 35511578
- Muraru D, Badano LP. Shedding new light on the right heart. Eur Heart J Cardiovasc Imaging 2022;23:863-6 doi: 10.1093/ehjci/jeac085. PMID: 35613037
- Kong WKF, Salsano A, Giacobbe DR, Popescu BA, Duval X, Schueler R, Moreo A, Colonna P, Piper C, Iglesias FC, Badano L, Srdanovic I, Boutoille D, Huttin O, Stoehr E, Timoteo AT, Vaskelyte J, Sadeghpour A, Habbal R, Abid L, Poh KK, Habib G, Lancellotti P. Outcomes of culture-negative versus culture-positive infective endocarditis: the ESC EORP EURO-ENDO registry. Eur Heart J 2022;43:2770-80 DOI: 10.1093/eurheartj/ehac307
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Sebag, I., Rudski, L., Ricafort, G., Barsic, B., Krajinovic, V., Vargovic, M., Separovic-Hanzevacki, J., Lovric, D., Reskovic-Luksic, V., Vincelj, J., Jurinjak, S.J., Yiannikourides, V., Ioannides, M., Kyriakou, C., Pofaides, C., Masoura, V., Yiangou, K., Pudich, J., Linhart, A., Siranec, M., Marek, J., Blechova, K., Kamenik, M., Pazdernik, M., Pelouch, R., Coufal, Z., Mikulica, M., Griva, M., Jancova, E., Mikulcova, M., Taborsky, M., Precek, J., Jecmenova, M., Latal, J., Widimsky, J., Butta, T., Machacek, S., Vancata, R., Spinar, J., Holicka, M., Long, F.P.C., Anzules, N., Carpio, A.B., Largacha, G., Penaherrera, E., Moreira, D., Mahfouz, E., Elsafty, E., Soliman, A., Zayed, Y., Aboulenein, J., Abdel-Hay, M., Almaghraby, A., Abdelnaby, M., Ahmed, M., Hammad, B., Saleh, Y., Zahran, H., Elgebaly, O., Saad, A., Ali, M., Zeid, A., Sharkawy, R.E., Meshaal, M., Al Kholy, A., Doss, R., Osama, D., Rizk, H., Elmogy, A., Mishriky, M., Assayag, P., Hatimi, S.E., Botelho-Nevers, S.-E., Campisi, S., Fuzellier, J.-F., Gagneux-Brunon, A., Pierrard, R., Tulane, C., Detoc, M., Mehalla, T., Boutoille, D., Al Habash, O., Asseray-Madani, N., Biron, C., Brochard, J., Caillon, J., Cueff, C., Le Tourneau, T., Lecompte, A.S., Lecomte, R., Lefebvre, M., Michel, M.M.M., Pattier, S., Delarue, S., Le Bras, M., Orain, J., Faucher, J.-F., Aboyans, V., Beeharry, A., Durox, H., Lacoste, M., Magne, J., Mohty, D., David, A., Pradel, V., Sierra, V., Neykova, A., Bettayeb, B., Elkentaoui, S., Tzvetkov, B., Landry, G., Strady, C., Ainine, K., Baumard, S., Brasselet, C., Tassigny, C., Valente-Pires, V., Lefranc, M., Hoen, B., Lefevre, B., Curlier, E., Callier, C., Fourcade, N., Jobic, Y., Ansard, S., Le Berre, R., Le Roux, P., Le Ven, F., Pouliquen, M.-C., Prat, G., Bouchart, F., Savoure, A., Alarcon, C., Chapuzet, C., Gueit, I., Tribouilloy, C., Bohbot, Y., Peugnet, F., Gun, M., Iung, B., Duval, X., Lescure, X., Ilic-Habensus, E., Sadoul, N., Selton-Suty, C., Alla, F., Chevalier, E., Goehringer, F., Huttin, O., Garcia, R., Le Marcis, V., Tattevin, P., Donal, E., Flecher, E., Revest, M., Habib, G., Hubert, S., Casalta, J.-P., Gouriet, F., Arregle, F., Cammilleri, S., Tessonnier, L., Riberi, A., Chirouze, C., Bouiller, K., Brunel, A.-S., Fournier, D., Hustache-Mathieu, L., Klopfenstein, T., Moreau, J., Lim, P., Oliver, L., Ternacle, J., Moussafeur, A., Chavanet, P., Piroth, L., Buisson, M., Mahy, S., Martins, C., Salmon-Rousseau, A., Gohier, S., Piper, C., Börgermann, J., Guckel, D., Horstkotte, D., Brockmeier, B., Winkelmann, E., Hagendorff, A., Grey, D., Nickenig, G., Schueler, R., Öztürk, C., Stöhr, E., Hamm, C., Walther, T., Brandt, R., Frühauf, A.-C., Hartung, C.T., Hellner, C., Wild, C., Becker, M., Hamada, S., Kaestner, W., Stangl, K., Knebel, F., Baldenhofer, G., Brecht, A., Dreger, H., Isner, C., Pfafflin, F., Stegemann, M., Zahn, R., Fraiture, B., Kilkowski, C., Karcher, A.-K., Klinger, S., Tolksdorf, H., Tousoulis, D., Aggeli, C., Sarri, G., Sideris, S., Venieri, E., Athanassopoulos, G., Tsiapras, D., Armenis, I., Koutsiari, A., Floros, G., Grassos, C., Dragasis, S., Rallidis, L., Varlamos, C., Michalis, L., Naka, K., Bechlioulis, A., Kotsia, A., Lakkas, L., Pappas, K., Papadopoulos, C., Kiokas, S., Lioni, A., Misailidou, S., Barbetseas, J., Bonou, M., Kapelios, C., Tomprou, I., Zerva, K., Manolis, A., Hamodraka, E., Athanasiou, D., Haralambidis, G., Poulimenos, L., Samaras, H., Nagy, A., Bartykowszki, A., Gara, E., Sengupta, S., Mungulmare, K., Kasliwal, R., Bansal, M., Bhan, A., Ranjan, S., Kyavar, M., Maleki, M., Bezanjani, F.N., Sadeghpour, A., Alizadehasl, A., Boudagh, S., Ghavidel, A., Moradnejad, P., Pasha, H.R., Ghadrdoost, B., Gilon, D., Strahilevitz, J., Israel, S., Wanounou, M., d’Agostino, C., Colonna, P., De Michele, L., Fumarola, F., Stante, M., Marchionni, N., Scheggi, V., Alterini, B., Del Pace, S., Stefano, P., Sparano, C., Badano, L.P., Muraru, D., Ruozi, N., Tenaglia, R., Limbruno, U., Cresti, A., Baratta, P., Solari, M., Giannattasio, C., Moreo, A., De Chiara, B., Montero, B.L., Musca, F., Orcese, C.A., Panzeri, F., Russo, C.F., Spano, F., Alfieri, O., De Bonis, M., Agricola, E., Busnardo, E., Carletti, S., Castiglioni, B., Chiappetta, S., Del Forno, B., Ferrara, D., Guffanti, M., Iaci, G., Lapenna, E., Nisi, T., Oltolini, C., Pajoro, U., Pasciuta, R., Ripa, M., Scarpellini, P., Din, C.T., Meneghin, R., Schiavi, D., Piscione, F., Citro, R., Benvenga, R.M., Greco, L., Prota, C., Radano, I., Soriente, L., Bellino, M., Di Vece, D., Santini, F., Salsano, A., Olivieri, G.M., Turrini, F., Messora, R., Tondi, S., Olaru, A., Agnoletto, V., Grassi, L., Leonardi, C., Sansoni, S., Del Ponte, S., Dato, G.M.A., De Martino, A., Ohte, N., Kikuchi, S., Wakami, K., Aonuma, K., Seo, Y., Ishizu, T., Machino-Ohtsuka, T., Yamamoto, M., Iida, N., Nakajima, H., Nakagawa, Y., Izumi, C., Amano, M., Miyake, M., Takahashi, K., Shiojima, I., Miyasaka, Y., Maeba, H., Suwa, Y., Taniguchi, N., Tsujimoto, S., Kitai, T., Ota, M., Yuda, S., Sasaki, S., Hagiwara, N., Yamazaki, K., Ashihara, K., Arai, K., Saitou, C., Saitou, S., Suzuki, G., Shibata, Y., Watanabe, N., Nishino, S., Ashikaga, K., Kuriyama, N., Mahara, K., Abe, K., Fujimaki, H., Okubo, T., Shitan, H., Takanashi, S., Terada, M., Yamamoto, H., Sata, M., Yamada, H., Kusunose, K., Saijo, Y., Seno, H., Yuichiro, O., Sakata, Y., Mizuno, H., Nakatani, S., Onishi, T., Sengoku, K., Sera, F., Park, S.W., Kyoung, K.E., Yeon, L.G., Hwang, J.-W., Jin-Oh, C., Park, S.-J., Sang-Chol, L., Sung-A, C., Jang, S.Y., Kang, D.-H., Heo, R., Lee, S., Song, J.-M., Jung, E., Plisiene, J., Dambrauskaite, A., Gruodyte, G., Jonkaitiene, R., Vaskelyte, J., Mizariene, V., Atkocaityte, J., Zvirblyte, R., Sow, R., Codreanu, A., De la Vega, E.C.L., Michaux, C., Staub, T., Jacobs-Orazi, L., Azzopardi, C.M., Xuereb, R.G., Piscopo, T., Borg, D., Casha, R., Farrugia, J., Fenech, M., Pllaha, E., Vella, C., Yamagata, K., Grib, L., Raevschi, E., Grejdieru, A., Balan, G., Cardaniuc, I., Cardaniuc, L., Corcea, V., Feodorovici, A., Gaina, V., Girbu, L., Jimbei, P., Kravcenco, D., Panfile, E., Prisacari, E., Samohvalov, E., Samohvalov, S., Sceglova, N., Benesco, I., Marian, V., Sumarga, N., Mirocevic, M., Bozovic, B., Bulatovic, N., Lakovic, P., Music, L., Roos-Hesselink, J., Budde, R., Gamela, T., Wahadat, A., Kamp, O., Meijers, T., Van Melle, J.P., Deursen, V.M., Crijns, H., Bekkers, S., Cheriex, E., Gilbers, M., Kietselaer, B., Knackstedt, C., Lorusso, R., Schalla, S., Streukens, S., Chamuleau, S., Cramer, M.-J., Teske, A., Van der Spoel, T., Wind, A., Liesbek, O., Lokhorst, J., Van Heusden, H., Tanis, W., Van der Bilt, I., Vriend, J., De Lange-van Bruggen, H., Karijodikoro, E., Riezebos, R., van Dongen, E., Schoep, J., Stolk, V., Axler, O., Baumann, F., Lebras, S., Edvardsen, T., Offstad, J.T., Beitnes, J.O., Helle-Valle, T., Skulstad, H., Skardal, R., Qamar, N., Furnaz, S., Ahmed, B., Butt, M.H., Khanzada, M.F., Saghir, T., Wahid, A., Hryniewiecki, T., Szymanski, P., Marzec, K., Misztal-Ogonowska, M., Kosmala, W., Przewlocka-Kosmala, M., Rojek, A., Woznicka, K., Zachwyc, J., Lisowska, A., Kaminska, M., Kasprzak, J., Kowalczyk, E., Strzecka, D.F., Wejner-Mik, P., Trabulo, M., Freitas, P., Ranchordas, S., Rodrigues, G., Pinto, P., Queiros, C., Azevedo, J., Marques, L., Seabra, D., Branco, L., Abreu, J., Cruz, M., Galrinho, A., Moreira, R., Rio, P., Timoteo, A.T., Selas, M., Cardim, N.M., Carmelo, V., Neves, B.D., Pereira, H., Cruz, I., Guerra, A., Marques, A., Pintassilgo, I., Tomescu, M.C., Trofenciuc, N.-M., Andor, M., Bordejevic, A., Branea, H.S., Caruntu, F., Cirin, L., Citu, I.M., Cotoraci, C.A., Darabantiu, D., Farcas, R., Marincu, I., Mavrea, A., Onel, M.F., Parvanescu, T., Pop, D., Pop-Moldovan, A.L., Puticiu, M.I., Velcean, L.A., Ionac, A., Cozma, D., Mornos, C., Goanta, F., Popescu, I., Beyer, R., Mada, R., Rancea, R., Rosianu, H., Tomoaia, R., Stanescu, C., Kobalava, Z., Karaulova, J., Kotova, E., Milto, A., Pisaryuk, A., Povalyaev, N., Sorokina, M., Alrahimi, J., Elshiekh, A., Jamiel, A., Ahmed, A., Al-Mallah, M., Attia, N., Putnikovic, B., Neskovic, A., Dimic, A., Ivanovic, B., Matic, S., Trifunovic, D., Petrovic, J., Kosevic, D., Dabic, P., Milojevic, P., Petrovic, I., Stojanovic, I., Srdanovic, I., Kovacevic, M., Redzek, A., Stefanovic, M., Susak, S., Velicki, L., Vulin, A., Yeo, T.C., Kong, W.K.F., Poh, K.K., Vilacosta, I., Nasser, M.A.E., Ferrera, C., Olmos, C., Iglesias, F.C., Blanco-Gonzalez, E., Amaro, M.B., Germinas, A.N., Lopez-Rodriguez, E., Adan, J.L., Pazos-Lopez, P., Loureiro, M.P., Perez, M.T., Raposeiras-Roubin, S., Yas, S.R., Suarez-Varela, M.-M., Vidal, F.V., Garcia-Dorado, D., Sambola, A., Fernandez-Hidalgo, N., Gonzalez-Alujas, T., Lozano, J., Maisterra, O., Pizzi, N., Rios, R., Tornos, P., Bayes-Genis, A., Botet, L.P., Vallejo, N., Berastegui, E., Llibre, C., Mateu, L., Nunez, R., Quesada, D., Portell, D.B., Vinas, J.A., Bertran, X.A., Tarradellas, R.B., Ricon, P.L.-O., de Llano, C.T., Arnau, M.A., Bel, A., Blanes, M., Osa, A., Anguita, M., Carrasco, F., Castillo, J., Zamorano, J.L., Mur, J.L.M., Alvaro, M., Fernandez-Golfin, C., Monteagudo, J.M., Elorza, E.N., Alvarez, M.C.F., Balbin, J.A., Arminanzas, C., de las Revillas, F.A., Garcia, A.A., Belaustegui, M.C., Sampedro, M.F., Cuadra, M.G., Gutierrez-Diez, J.F., Zarauza, J., Cuello, L.G., Rico, C.G., Rodriguez-Alvarez, R., Goikoetxea, J., Montejo, M., Miro, J., Almela, M., Ambrosioni, J., Falces, C., Fuster, D., Garcia-de-la-Maria, C., Hernandez-Meneses, M., Llopis, J., Marco, F., Moreno, A., Quintana, E., Sandoval, E., Tellez, A., Tolosana, J.M., Vidal, B., Ruiz-Zamora, I., Ruiz, A.B., Girgas, E.S., Garcia-Pardo, G., Marzo, M.G., Oviedo, A.R., Jimenez, A.V., Abid, L., Hammami, R., Kammoun, S., Mourali, M.S., Zghal, F.M., Hlima, M.B., Boudiche, S., Ouali, S., Zakhama, L., Antit, S., Slama, I., Gulel, O., Sahin, M., Sade, L.E., Karacaglar, E., Kucukoglu, S., Cetinarslan, O., Yasar, U.S., Canpolat, U., Mutlu, B., Atas, H., Dervishova, R., Ileri, C., Zaky, H., Alhashmi, J., Baslib, F., Tahir, J., Zarger, P., Woldman, S., Menezes, L., Primus, C., Uppal, R., Bvekerwa, I., Chandrasekaran, B., Kopanska, A., Prendergast, B., Cannata, S., Chambers, J., Hancock, J., Klein, J., Rajani, R., Ursi, M.P., Dworakowski, R., Fife, A., Breeze, J., Browne-Morgan, M., Gunning, M., Streather, S., Asch, F., Zemedkun, M., Alyavi, B., Uzokov, J., the EURO-ENDO Investigators group. Surgery and outcome of infective endocarditis in octogenarians: prospective data from the ESC EORP EURO-ENDO registry. Infection 2022;50:1191-1202. DOI 10.1007/s15010-022-01792-0 PMID: 35290614
- Tomaselli M, Badano LP, Menè R, Gavazzoni M, Heilbron F, Radu N, Caravita S, Baratto C, Oliverio G, Florescu DR, Parati G, Muraru D. Impact of correcting the 2D PISA method on the quantification of functional tricuspid regurgitation severity. Eur Heart J Cardiovasc Imaging. 2022;23:1459-1470. doi: 10.1093/ehjci/jeac104. PMID: 35734964.
- Muscogiuri G, Volpato V, Cau R, Chiesa M, Saba L, Guglielmo M, Senatieri A, Chierchia G, Pontone G, Dell'Aversana S, Schoepf UJ, Andrews MG, Basile P, Guaricci AI, Marra P, Muraru D, Badano LP, Sironi S. Application of AI in cardiovascular multimodality imaging. Heliyon. 2022;8:e10872. doi: 10.1016/j.heliyon.2022.e10872. PMID: 36267381
- Hosseini S, Samiei N, Tabib A, Bakhshandeh H, Rezaei Y, Parsaee M, Rashidi Ghader F, Moradian M, Shojaeifard M, Khajali Z, Taghavi S, Naderi N, Mortaz Hejri G, Ghaderian H, Houshmand G, Kaviani R, Farrashi M, Pakbaz M, Mombeini H, Saedi S, Ghavidel AA, Omrani G, Mohebbi A, Peighambari MM, Khorgami MR, Nikpajouh A, Amin A, Maleki M, Mestres CA, Badano LP, Noohi F; Shed Light Investigators. Prevalence of Structural Heart Diseases Detected by Handheld Echocardiographic Device in School-Age Children in Iran: The SHED LIGHT Study. Glob Heart. 2022;17:39. doi: 10.5334/gh.1121. PMID: 35837354
- Volpato V, Ciampi P, Johnson R, Hipke K, Tomaselli M, Oliverio G, Muraru D, Badano LP, Lang RM. Feasibility and Time Analysis of Three-Dimensional and Myocardial Deformation versus Conventional Two-Dimensional Echocardiography to Assess Cardiac Chambers. J Am Soc Echocardiogr. 202235:1102-1105. doi: 10.1016/j.echo.2022.05.017. PMID: 35690298
- Soliman-Aboumarie H, Joshi SS, Cameli M, Michalski B, Manka R, Haugaa K, Demirkiran A, Podlesnikar T, Jurcut R, Muraru D, Badano LP, Dweck MR. EACVI survey on the multi-modality imaging assessment of the right heart. Eur Heart J Cardiovasc Imaging. 2022;23:1417-1422. doi: 10.1093/ehjci/jeac183. PMID: 36093580.
- Muraru D, Gavazzoni M, Heilbron F, Mihalcea DJ, Guta AC, Radu N, Muscogiuri G, Tomaselli M, Sironi S, Parati G, Badano LP. Reference ranges of tricuspid annulus geometry in healthy adults using a dedicated three-dimensional echocardiography software package. Front Cardiovasc Med. 2022;9:1011931. doi: 10.3389/fcvm.2022.1011931. PMID: 36176994
- Badano LP, Surkova E, Muraru D. Letter to the editor regarding 'Cardiac magnetic resonance for prophylactic implantable-cardioverter defibrillator therapy international study: prognostic value of cardiac magnetic resonance-derived right ventricular parameters substudy'. Eur Heart J Cardiovasc Imaging. 2022;23:e477-e478. doi: 10.1093/ehjci/jeac159. PMID: 35946058
- Baratto C, Caravita S, Soranna D, Dewachter C, Bondue A, Zambon A, Badano LP, Parati G, Vachiéry JL. Exercise haemodynamics in heart failure with preserved ejection fraction: a systematic review and meta-analysis. ESC Heart Fail. 2022. doi: 10.1002/ehf2.13979. PMID: 35748109
- Galiñanes M, Casós K, Blasco-Lucas A, Permanyer E, Máñez R, Le Tourneau T, Barquinero J, Schwartz S Jr, Roussel TBJC, Fellah-Hebia I, Sénage T, Evangelista A, Badano LP, Ruiz-Majoral A, Galli C, Padler-Karavani V, Soulillou JP, Vidal X, Cozzi E, Costa C. Oxidative Stress in Structural Valve Deterioration: A Longitudinal Clinical Study. Biomolecules. 2022;12:1606. doi: 10.3390/biom12111606. PMID: 36358956
- Gavazzoni M, Heilbron F, Badano LP, Radu N, Cascella A, Tomaselli M, Perelli F, Caravita S, Baratto C, Parati G, Muraru D. The atrial secondary tricuspid regurgitation is associated to more favorable outcome than the ventricular phenotype. Front Cardiovasc Med. 2022;9:1022755. doi: 10.3389/fcvm.2022.1022755 PMID: 36523369
- Lee L, Cotella JI, Miyoshi T, Addetia K, Schreckenberg M, Hitschrich N, Blankenhagen M, Amuthan V, Citro R, Daimon M, Gutiérrez-Fajardo P, Kasliwal R, Kirkpatrick JN, Monaghan MJ, Muraru D, Ogunyankin KO, Park SW, Tude Rodrigues AC, Ronderos R, Sadeghpour A, Scalia GM, Takeuchi M, Tsang W, Tucay ES, Zhang M, Mor-Avi V, Asch FM, Lang RM; WASE Study Investigators. Normal Values of Left Ventricular Mass by 2D and 3D Echocardiography: Results from the World Alliance Societies of Echocardiography Normal Values Study. J Am Soc Echocardiogr. 2022:S0894-7317(22)00674-5. doi: 10.1016/j.echo.2022.12.016
- Muraru D, Baldea SM, Genovese D, Tomaselli M, Heilbron F, Gavazzoni M, Radu N, Sergio C, Baratto C, Perelli F, Curti E, Parati G, Badano LP. Association of outcome with left ventricular volumes and ejection fraction measured with two- and three-dimensional echocardiography in patients referred for routine, clinically indicated studies. Front Cardiovasc Med. 2022;9:1065131. doi: 10.3389/fcvm.2022.1065131. PMID: 36620642
- Baratto C, Caravita S, Soranna D, Dewachter C, Bondue A, Zambon A, Badano LP, Parati G, Vachiéry JL. An updated meta-analysis of hemodynamics markers of prognosis in patients with pulmonary hypertension due to left heart disease. Pulm Circ. 2022 Oct 1;12(4):e12145. doi: 10.1002/pul2.12145. PMID: 36568693;
- Singulane CC, Miyoshi T, Mor-Avi V, Cotella JI, Schreckenberg M, Blankenhagen M, Hitschrich N, Addetia K, Amuthan V, Citro R, Daimon M, Gutiérrez-Fajardo P, Kasliwal R, Kirkpatrick JN, Monaghan MJ, Muraru D, Ogunyankin KO, Park SW, Tude Rodrigues AC, Ronderos R, Sadeghpour A, Scalia GM, Takeuchi M, Tsang W, Tucay ES, Zhang Y, Asch FM, Lang RM. Age-, Sex-, and Race-Based Normal Values for Left Ventricular Circumferential Strain from the World Alliance Societies of Echocardiography Study. J Am Soc Echocardiogr. 2022 Dec 30:S0894-7317(22)00702-7. doi: 10.1016/j.echo.2022.12.018. Epub ahead of print. PMID: 36592875.
- Benfari G, Mandoli GE, Magne J, Miglioranza MH, Ancona R, Luksic VR, Pastore MC, Santoro C, Michalski B, Malagoli A, Muraru D, Donal E, Cosyns B, Edvardsen T, Popescu BA, Cameli M; MASCOT investigators. Left atrial strain determinants and clinical features according to the heart failure stages. New insight from EACVI MASCOT registry. Int J Cardiovasc Imaging. 2022 Dec;38(12):2635-2644. doi: 10.1007/s10554-022-02669-x. Epub 2022 Jul 1. PMID: 36445656
- Muraru D. 22nd Annual Feigenbaum Lecture: Right Heart, Right Now: The Role of Three-Dimensional Echocardiography. J Am Soc Echocardiogr. 2022 Sep;35(9):893-909. doi: 10.1016/j.echo.2022.05.011. Epub 2022 May 26. PMID: 35644303
- Henry MP, Cotella J, Mor-Avi V, Addetia K, Miyoshi T, Schreckenberg M, Blankenhagen M, Hitschrich N, Amuthan V, Citro R, Daimon M, Gutiérrez-Fajardo P, Kasliwal R, Kirkpatrick JN, Monaghan MJ, Muraru D, Ogunyankin KO, Park SW, Tude Rodrigues AC, Ronderos R, Sadeghpour A, Scalia G, Takeuchi M, Tsang W, Tucay ES, Zhang M, Lang RM, Asch FM. Three-Dimensional Transthoracic Static and Dynamic Normative Values of the Mitral Valve Apparatus: Results from the Multicenter World Alliance Societies of Echocardiography Study. J Am Soc Echocardiogr. 2022 Jul;35(7):738-751.e1. doi: 10.1016/j.echo.2022.02.010. Epub 2022 Mar 1. PMID: 35245668.
- Muraru D, Haugaa K, Donal E, Stankovic I, Voigt JU, Petersen SE, Popescu BA, Marwick T. Right ventricular longitudinal strain in the clinical routine: a state-of-the-art review. Eur Heart J Cardiovasc Imaging. 2022 Jun 21;23(7):898-912. doi: 10.1093/ehjci/jeac022. PMID: 35147667
- Sade LE, Muraru D, Marsan NA, Agricola E, Stankovic I, Donal E. How to assess severe tricuspid regurgitation by echocardiography? Eur Heart J Cardiovasc Imaging. 2022 Sep 10;23(10):1273-1276. doi: 10.1093/ehjci/jeac015. PMID: 35136997
- Carvalho Singulane C, Singh A, Miyoshi T, Addetia K, Soulat-Dufour L, Schreckenberg M, Blankenhagen M, Hitschrich N, Amuthan V, Citro R, Daimon M, Gutiérrez-Fajardo P, Kasliwal R, Kirkpatrick JN, Monaghan MJ, Muraru D, Ogunyankin KO, Park SW, Tude Rodrigues AC, Ronderos R, Sadeghpour A, Scalia GM, Takeuchi M, Tsang W, Tucay ES, Zhang Y, Mor-Avi V, Asch FM, Lang RM. Sex-, Age-, and Race-Related Normal Values of Right Ventricular Diastolic Function Parameters: Data from the World Alliance Societies of Echocardiography Study. J Am Soc Echocardiogr. 2022;35:426-434. doi: 10.1016/j.echo.2021.10.006. PMID: 34695547.
- Patel HN, Miyoshi T, Addetia K, Citro R, Daimon M, Gutierrez Fajardo P, Kasliwal RR, Kirkpatrick JN, Monaghan MJ, Muraru D, Ogunyankin KO, Park SW, Ronderos RE, Sadeghpour A, Scalia GM, Takeuchi M, Tsang W, Tucay ES, Tude Rodrigues AC, Amuthan V, Zhang Y, Schreckenberg M, Blankenhagen M, Degel M, Hitschrich N, Mor-Avi V, Asch FM, Lang RM; WASE Investigators. Normal Values of Aortic Root Size According to Age, Sex, and Race: Results of the World Alliance of Societies of Echocardiography Study. J Am Soc Echocardiogr. 2022 Mar;35(3):267-274. doi: 10.1016/j.echo.2021.09.011. PMID: 34619294;
2023
- Kemaloğlu Öz T, Badano LP. Can three-dimensional echocardiography change the game for the pulmonary valve? Eur Heart J. 2023 Mar 1;44(9):703-705. doi: 10.1093/eurheartj/ehac772. PMID: 36593227.
- Merlo M, Gagno G, Baritussio A, Bauce B, Biagini E, Canepa M, Cipriani A, Castelletti S, Dellegrottaglie S, Guaricci AI, Imazio M, Limongelli G, Musumeci MB, Parisi V, Pica S, Pontone G, Todiere G, Torlasco C, Basso C, Sinagra G, Filardi PP, Indolfi C, Autore C, Barison A. Clinical application of CMR in cardiomyopathies: evolving concepts and techniques : A position paper of myocardial and pericardial diseases and cardiac magnetic resonance working groups of Italian society of cardiology. Heart Fail Rev. 2023;28:77-95. doi: 10.1007/s10741-022-10235-9. PMID: 35536402;
- Tondi L, Badano LP, Figliozzi S, Pica S, Torlasco C, Camporeale A, Florescu DR, Disabato G, Parati G, Lombardi M, Muraru D. The use of dedicated long-axis views focused on the left atrium improves the accuracy of left atrial volumes and emptying fraction measured by cardiovascular magnetic resonance. J Cardiovasc Magn Reson. 2023;25:10. doi: 10.1186/s12968-022-00905-w. PMID: 36793062
- Figliozzi S, Georgiopoulos G, Lopes PM, Bauer KB, Moura-Ferreira S, Tondi L, Mushtaq S, Censi S, Pavon AG, Bassi I, Servato ML, Teske AJ, Biondi F, Filomena D, Pica S, Torlasco C, Muraru D, Monney P, Quattrocchi G, Maestrini V, Agati L, Monti L, Pedrotti P, Vandenberk B, Squeri A, Lombardi M, Ferreira AM, Schwitter J, Aquaro GD, Chiribiri A, Rodríguez Palomares JF, Yilmaz A, Andreini D, Florian A, Leiner T, Abecasis J, Badano LP, Bogaert J, Masci PG. Myocardial Fibrosis at Cardiac MRI Helps Predict Adverse Clinical Outcome in Patients with Mitral Valve Prolapse. Radiology. 2023;306:112-121. doi: 10.1148/radiol.220454. PMID: 36098639
- Genovese D, Previtero M, Prete G, Carrer A, De Michieli L, Badano LP, Muraru D, Cernetti C, Mele D, Tarantini G, Iliceto S, Perazzolo Marra M. Non-invasive evaluation of pulmonary capillary wedge pressure using the left atrial expansion index in mitral valve stenosis, prosthesis and repair. Int J Cardiovasc Imaging. 2023 Feb 10. doi: 10.1007/s10554-023-02807-z. Epub ahead of print. PMID: 36763208.
- Ciampi P, Badano LP, Florescu DR, Villella F, Tomaselli M, Torlasco C, Gavazzoni M, Parati G, Muraru D. Comparison of RA Volumes Obtained Using the Standard Apical 4-Chamber and the RV-Focused Views. JACC Cardiovasc Imaging. 2023 Feb;16(2):248-250. doi: 10.1016/j.jcmg.2022.08.018. PMID: 36648037.
- Papetti DM, Van Abeelen K, Davies R, Menè R, Heilbron F, Perelli FP, Artico J, Seraphim A, Moon JC, Parati G, Xue H, Kellman P, Badano LP, Besozzi D, Nobile MS, Torlasco C. An accurate and time-efficient deep learning-based system for automated segmentation and reporting of cardiac magnetic resonance-detected ischemic scar. Comput Methods Programs Biomed. 2023;229:107321 doi: 10.1016/j.cmpb.2022.107321. PMID: 36586175.
- Genovese D, Badano LP, Perazzolo Marra M. Left atrial volume and left ventricular mass for pulmonary capillary wedge pressure assessment with cardiovascular magnetic resonance: accurate enough for clinical use? Eur Heart J. 2023 Feb 1;44(5):425-426. doi: 10.1093/eurheartj/ehac739. PMID: 36514969
- Baratto C, Caravita S, Corbetta G, Soranna D, Zambon A, Dewachter C, Gavazzoni M, Heilbron F, Tomaselli M, Radu N, Perelli FP, Perego GB, Vachiéry JL, Parati G, Badano LP, Muraru D. Impact of severe secondary tricuspid regurgitation on rest and exercise hemodynamics of patients with heart failure and a preserved left ventricular ejection fraction. Front Cardiovasc Med. 2023;10:1061118. doi: 10.3389/fcvm.2023.1061118. PMID: 36937944
- Meuris B, Günaydın S, Lancellotti P, Badano L, Aldea G, Herrenknecht R, Cerutti E, Gaggianesi S, Dipinto S, Morando P, Kempfert J. The MANTRA study: a new umbrella concept prospectively applied to assess implantable medical devices for heart valve procedures. J Cardiothorac Surg. 2023 Apr 7;18(1):110. doi: 10.1186/s13019-023-02270-w. PMID: 37029428.
- Tun HN, Almaghraby A, Kavalerchyk V, Muraru D, Soliman-Aboumarie H, Abdelnabi M. Acute Right Ventricular Failure: Pathophysiology, diagnostic approach with emphasis on the role of echocardiography. Curr Cardiol Rev. 2023 doi: 10.2174/1573403X19666230206115611. Epub ahead of print. PMID: 36748814.
- Sorrell VL, Lindner JR, Pellikka PA, Kirkpatrick JN, Muraru D. Recognized and Unrecognized Value of Echocardiography in Guideline and Consensus Documents Regarding Patients With Chest Pain. J Am Soc Echocardiogr. 2023 Feb;36(2):146-153. doi: 10.1016/j.echo.2022.10.024. Epub 2022 Nov 11. PMID: 36375734.
- Cotella JI, Miyoshi T, Mor-Avi V, Addetia K, Schreckenberg M, Sun D, Slivnick JA, Blankenhagen M, Hitschrich N, Amuthan V, Citro R, Daimon M, Gutiérrez-Fajardo P, Kasliwal R, Kirkpatrick JN, Monaghan MJ, Muraru D, Ogunyankin KO, Park SW, Tude Rodrigues AC, Ronderos R, Sadeghpour A, Scalia G, Takeuchi M, Tsang W, Tucay ES, Zhang M, Prado AD, Asch FM, Lang RM. Normative values of the aortic valve area and Doppler measurements using two-dimensional transthoracic echocardiography: results from the Multicentre World Alliance of Societies of Echocardiography Study. Eur Heart J Cardiovasc Imaging. 2023 Mar 21;24(4):415-423. doi: 10.1093/ehjci/jeac220. PMID: 36331816
- Pezel T, Coisne A, Michalski B, Soliman H, Ajmone N, Nijveldt R, Stankovic I, Donal E, van der Maaten J, Papadopoulos C, Edvardsen T, Muraru D, Petersen SE, Cosyns B, Bäck M, Bertrand PB, Haugaa KH, Keenan N, Donal E, Cosyns B. EACVI SIMULATOR-online study: evaluation of transoesophageal echocardiography knowledge and skills of young cardiologists. Eur Heart J Cardiovasc Imaging. 2023 Feb 17;24(3):285-292. doi: 10.1093/ehjci/jeac195. PMID: 36151868.
Progetti di ricerca finanziati con partecipazione a bandi competitivi
- Bando Ricerca Finalizzata 2021 (fondi 2020-2021) Progetto# RF-2021-12374122.di tipo …Theory-enhancing dal titolo “In-depth characterization of atriogenic secondary tricuspid regurgitation due to atrial fibrillation. Prevalence, mechanisms, advanced quantification of regurgitation severity, and relative impact of sinus rhythm restoration on the 3D remodeling of right heart chambers and tricuspid valve apparatus “
https://www.salute.gov.it/portale/ministro/p4_10_1_1_atti_1_1.jsp?lingu… - Bando PNRR 2022. Progetto codice .PNRR-MAD-2022-12375700.nella sezione Malattie Croniche non Trasmissibili (MCnT) ad alto impatto sui sistemi sanitari e socio-assistenziali dal titolo “ Use of intepREtable artificial intelligence techniqueS for a PErsonalized risk prediCTion of sudden cardiac death in patients with ischemic and non-ischemic left ventricular dysfunction.The RESPECT project” https://www.salute.gov.it/portale/ministro/p4_10_1_1_atti_1_1.jsp?lingu…
- Research project funded by the Italian Ministry of Health CC-2019-2366577_001 - Cat. II (EX C)-Aggr. IRCCS- INTEGRATION OF 3D CARDIOVASCULAR IMAGING AND EXTENDED REALITY APPLICATIONS (AUGMENTED REALITY AND VIRTUAL REALITY) FOR THE CREATION OF VIRTUAL HEART TEAMS BETWEEN PROFESSIONALS FROM DIFFERENT INSTITUTIONS, TO SUPPORT PATINT SELECTION AND PLANNING OF CARDIAC SURGERY OR STRUCTURAL INTERVENTIONS-Procedura DGRIC n. 1944 del 25/05/2020 - IRCCS CC 2019-20
- Research project funded by Fondazione Vollaro (ID= 2021-NOECO-0008) CARDIAC STRUCTURE REMODELING IN ATRIAL FIBRILLATION AND EFFECTS OF SINUS RHYTHM RESTORATION
Awards
La professoressa Muraru è vice-presidente e coordinatrice della sezione ecocardiografia della European Association of Cardiovascular Imaging.
Il prof Badano è il coordinatore del gruppo di studio cardiopatie valvolari della Società Italiana di Cardiologia.
3 membri dello staff del laboratorio di ecocardiografia hanno ricevuto la certificazione di competenza della European Association of Cardiovascular Imaging.
PRINCIPALI COLLABORAZIONI A NETWORK DI RICERCA NAZIONALI E INTERNAZIONALI
Gruppo di studio su cardiopatie valvolari della Società Italiana di Cardiologia
Gruppo di studio su risonanza magnetica cardiaca della Società Italiana di Cardiologia
World Alliance Societies of Echocardiography Normal Values Study
European Society of Cardiology EORP EURO-ENDO registry
Gruppo di studio AC-TIVE per la diagnosi ecocardiografica dell’amiloidosi cardiaca.